Typhoid IgG IgM Rapid Test Kit

Short Description:

A rapid test for the qualitative detection of IgG and IgM antibodies to Salmonella typhi (S. typhi) in human serum or plasma.


MOQ:1000 pcs


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SUMMARY

  Typhoid fever is caused by S. typhi, a Gram-negative bacterium. World-wide an estimated 17 million cases and 600,000 associated deaths occur annually1 . Patients who are infected with HIV are at significantly increased risk of clinical infection with S. typhi2 . Evidence of h. pylori infection also presents an increase risk of acquiring typhoid fever. 1-5% of patients become chronic carrier harboring S. typhi in the gallbladder. The clinical diagnosis of typhoid fever depends on the isolation of S. typhi from blood, bone marrow or a specific anatomic lesion in the facilities that cannot afford to perform this complicated and time consuming procedure, Widal Test (also referred as Weil-Felix Test) is used to facilitate the diagnosis. However, many limitations lead to difficulties in the interpretation of the Widal test . In contrast, the Typhoid Rapid Test Cassette is a simple and rapid laboratory test. The test simultaneously detects and differentiates the IgG and the IgM antibodies to S. typhi specific antigen in serum or plasma thus aid in the determination of current or previous exposure the S. typhi


PRINCIPLE

  The Typhoid Rapid Test Cassette is a qualitative, membrane based immunoassay for the detection of antibodies (IgG and IgM) to Salmonella typhi (S. typhi) in human serum or plasma. The diagnostic test cassette consists of two components: an IgG component and an IgM component. The IgG line region is pre-coated with reagents for the detection of anti-S. typhi (IgG). The IgM line region is pre-coated with monoclonal anti-human IgM for detection of anti-S. typhi (IgM).During testing, specimen dispensed into the sample well of the test cassette binds with Typhoid conjugates impregnated in the reagent area, if the specimen contains anti-Typhoid antibodies. The immunocomplex thus formed migrates by capillary action. If the present antibodies in specimen are of IgG types, the immunocomplex is then captured by the pre-coated reagents on the membrane, forming a colored IgG line, indicating a S. typhi IgG positive test result. If the present antibodies in the specimen are of IgM type, the immunocomplex would be captured on the membrane by the pre-coated anti-human IgM antibody, forming a colored IgM line, indicating a S. typhi IgM positive test result.Absence of any T lines (IgM and IgG) indicates a negative result. A colored control line (C) should always appear in case of a positive or a negative result. Its absence indicates invalid test results.

STORAGE AND STABILITY

  Store as packaged in the sealed pouch at room temperature or refrigerated (4-30℃). The test is stable through the expiration date printed on the sealed pouch. The test must remain in the sealed pouch until use. DO NOT FREEZE. Do not use beyond the expiration date.

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