Teetanada waa cudur dilaa ah oo ay keento bakteeriyada anaerobic Gram-positive bakteeriyada magaceeda la yiraahdo Clostridium tetani, taas oo soo saari karta teetanada exotoxin taas oo xannibi karta synapses-ka xannibaya dareemayaasha dareemayaasha ee habka dhexe ee neerfayaasha (CNS). Waqtigan xaadirka ah, qaabka ugu waxtarka badan ee looga hortago cudurka teetanada waa tallaalka teetanada aadanaha ee ka hortagga unugyada immunoglobulin ama teetanada toxoid. Heerka difaaca jirka ee teetanada ka dib tallaalka jirka bini'aadamka ayaa tilmaamaya difaaca qofka, iyo dadka leh heer ka hooseeya heerka ugu hooseeya (0.01 IU/ml) waxay leeyihiin halis dilaa ah in lagu qaado teetanada, gaar ahaan haddii ay dhacdo dhaawac. Marka loo eego WHO, heerka difaaca ka hortagga teetanada ee waxtarka leh waa 0.1IU/ml. Ogaanshaha heerarka ka hortagga teetanada ayaa lagama maarmaan u ah labadaba go'aaminta heerka difaaca shakhsiyaadka iyo sidoo kale qorsheynta tallaabooyinka ka hortagga.

 

Sida teetanada si degdeg ah oo sax ah loogu baaro teetanada ayaa had iyo jeer caqabad weyn ku ahayd daaweeyayaasha ku takhasusay dhinaca daawaynta. Dhawaan, Hysen Biotech Inc. waxay ku dhawaaqday bilawga teetanada cusub ee tijaabada degdega ah - Hysen Tetanus Antibody Rapid Test. Habkani waxa uu daqiiqado gudahood ku ogaan karaa sunta teetanada, taas oo si weyn u soo gaabinaysa wakhtiga loo baahan yahay ogaanshaha shaybaadhka dhaqameed.

Hysen Tetanus Antibody-ka Cassette ee Degdegga ah (Dhiigga Dhan/ Serum/Balaasmaha) waa xuub tayo leh oo ku salaysan immunoassay si loo ogaado unugyada difaaca jirka ee sunta teetanada ee ku jirta dhiigga bini'aadamka oo dhan, serum, ama balasmaha. Nidaamkan tijaabada ah, Ka-hortagga aadanaha IgG waxaa lagu dahaadhay gobolka khadka tijaabada. Inta lagu jiro tijaabada, muunadu waxay ka falcelinaysaa teetanada sunta antigen-ka ee ku jira cajaladda tijaabada. Isku darka ayaa markaa kor ugu guura xuubka chromatographically iyadoo la raacayo ficil capillary waxayna la falgalaan ka-hortagga bini'aadamka IgG ee gobolka khadka tijaabada. Haddii muunada ay ka kooban tahay unugyada difaaca jirka ee teetanada, xariiq midabaysan ayaa ka soo bixi doona gobolka khadka tijaabada. Sidaa darteed, haddii shaybaarku ka kooban yahay unugyada difaaca jirka ee teetanada, xariiq midabaysan ayaa ka soo bixi doona gobolka xariiqda tijaabada. Haddii muunada aysan ku jirin unugyada difaaca jirka ee teetanada, xarriiq midab leh kama soo bixi doono gobollada xariiqda tijaabada, taasoo muujineysa natiijo xun. Si loogu adeego sida habraaca kontoroolka, xariiq midabaysan ayaa had iyo jeer ka soo muuqan doona gobolka xariiqda kantaroolka, taas oo muujinaysa in mugga saxda ah ee muunada lagu daray iyo in xuub go'ay uu dhacay.

 

Xaqiijinta kiliinikada ee Hysen Tetanus Antibody-ka degdega ah waxay muujinaysaa natiijooyin cajiib ah. Daraasad dhowaan la sameeyay oo ku lug lahayd in ka badan 300 bukaan, Hysen Tetanus Antibody Test Degdegga ah ayaa helay dareenka qaraabada: 100%; Gaar ahaan Qaraabada: 96.3%; Sax ah:96.9% marka la barbar dhigo xirmooyinka ELIZA.

 

Soo bandhigida Hysen Tetanus Kahortagga Jirka Baaritaanka Degdega ah waxay saameyn weyn ku leedahay hal-abuurka caafimaadka adduunka. Teetanada ayaa weli ah arrin caafimaad dadweyne oo halis ah dalal badan oo dakhligoodu hooseeyo iyo kuwa dhexdhexaadka ah, halkaasoo helitaanka degdegga ah iyo ogaanshaha saxda ah ay xaddidan tahay. Helitaanka tijaabadan degdega ah kaliya ma wanaajinayso natiijooyinka bukaanka laakiin sidoo kale waxay yaraynaysaa culayska nidaamyada daryeelka caafimaadka iyadoo la hagaajinayo habka ogaanshaha.

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Waqtiga boostada: 2024-02-06