Kafumbata ndi matenda oopsa amene amayamba chifukwa cha bakiteriya anaerobic Gram-positive wotchedwa Clostridium tetani, amene amatha kutulutsa exotoxin ya kafumbata yomwe imatha kutsekereza ma synapses oletsa kuphatikizika kwa ma motor neurons mu dongosolo lapakati lamanjenje (CNS). Pakali pano, njira yabwino kwambiri yothanirana ndi matenda a kafumbata ndi katemera wa kafumbata wamunthu amene amateteza thupi ku immunoglobulin kapena kafumbata toxoid. Mlingo wa katemera wa kafumbata pambuyo polandira katemera m'thupi la munthu umasonyeza chitetezo cha munthu, ndipo anthu omwe ali ndi chitetezo chochepa kwambiri (0.01 IU/mL) ali ndi chiopsezo choopsa chotenga kafumbata, makamaka akavulala. Malinga ndi WHO, mulingo wa antibody oteteza kafumbata ndi 0.1IU/ml. Kuzindikira kuchuluka kwa ma anti-tetanus antibody ndikofunikira kuti mudziwe momwe chitetezo cha mthupi cha munthu chilili komanso pokonzekera njira zodzitetezera.

 

Momwe mungadziwire kafumbata mwachangu komanso molondola nthawi zonse kwakhala vuto lalikulu kwa asing'anga apadera pazamankhwala. Posachedwapa, Hysen Biotech Inc. yalengeza kukhazikitsidwa kwa njira yatsopano yoyesera kafumbata mofulumira - Hysen Tetanus Antibody Rapid Test. Njirayi imatha kuzindikira poizoni wa kafumbata mkati mwa mphindi zochepa, kufupikitsa kwambiri nthawi yofunikira pakuzindikiritsa zasayansi zaku labotale.

The Hysen Tetanus Antibody Rapid Test Cassette (Magazi Onse/Seramu/Magazi a Plasma) ndi nembanemba yoyeserera yodziwikiratu kuti ma antibodies ku poizoni wa kafumbata m'magazi athunthu a munthu, seramu, kapena madzi a m'magazi. Munjira yoyesera iyi, Anti-human IgG imakutidwa mumzere woyeserera. Pakuyesa, chitsanzocho chimakumana ndi tinthu tating'onoting'ono ta kafumbata toxin antigen mu kaseti yoyesera. Kusakaniza kumasunthira pamwamba pa nembanemba chromatographically ndi capillary action ndikuchita ndi anti-anthu IgG m'chigawo cha mayeso. Ngati chitsanzocho chili ndi ma antibodies ku kafumbata kafumbata, mzere wachikuda udzawonekera pagawo loyesera. Choncho, ngati chitsanzocho chili ndi ma antibodies ku kafumbata kafumbata, mzere wachikuda udzawonekera pagawo loyesera. Ngati chitsanzocho chilibe ma antibodies ku kafumbata kafumbata, palibe mzere wamitundu womwe udzawonekere m'magawo oyeserera, zomwe zikuwonetsa zotsatira zoyipa. Kuti ikhale ngati njira yoyendetsera, mzere wachikuda udzawonekera nthawi zonse m'chigawo cha mzere wolamulira, kusonyeza kuti chiwerengero choyenera cha chitsanzo chawonjezeredwa ndipo kupukuta kwa membrane kwachitika.

 

Kutsimikizika kwachipatala kwa Hysen Tetanus Antibody Rapid Test kukuwonetsa zotsatira zochititsa chidwi. Mu kafukufuku waposachedwapa wokhudza odwala 300, Hysen Tetanus Antibody Rapid Test anapeza Relative Sensitivity: 100%; Zachibale: 96.3%; Kulondola: 96.9% poyerekeza ndi zida za ELIZA.

 

Kuyambitsa kwa Hysen Tetanus Antibody Rapid Test kuli ndi tanthauzo lalikulu pakupanga thanzi lapadziko lonse lapansi. Kafumbata kakadali vuto lalikulu la thanzi la anthu m'mayiko ambiri omwe ali ndi ndalama zochepa komanso zapakati, kumene kupezeka kwa matenda mwamsanga ndi molondola kumakhala kochepa. Kupezeka kwa mayesero ofulumirawa sikumangowonjezera zotsatira za odwala komanso kumachepetsanso zolemetsa pa machitidwe a zaumoyo mwa kuwongolera njira yowunikira.

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Nthawi yotumiza: 2024-02-06