H.pylori Antigen Test

Short Description:

A rapid test for the qualitative detection of Helicobacter pylori (H. pylori) antigens in human feces.

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【SUMMARY】

H. pylori is a small, spiral-shaped bacterium that lives in the surface of the stomach and duodenum. It is implicated in the etiology of a variety of gastrointestinal diseases, including duodenal and gastric ulcer, non-ulcer dyspepsia and active and chronic gastritis.1,2 Both invasive and non-invasive methods are used to diagnose H. pylori infection in patients with symptoms of gastrointestinal disease. Specimendependent and costly invasive diagnostic methods include gastric or duodenal biopsy followed by urease testing (presumptive), culture, and/or histologic staining.3 A very common approach to the diagnosis of H. pylori infection is the serological identification of specific antibodies in infected patients. The main limitation of serology test is the inability to distinguish current and past infections. Antibody may be present in the patient’s serum long after eradication of the organisms.4 HpSA (H. pylori Stool Antigen) testing is gaining popularity for diagnosis of H. pylori infection and also for monitoring the efficacy of the treatment of H. pylori infection. Studies have found that more than 90% of patients with duodenal ulcer and 80% of patients with gastric ulcer are infected with H. pylori.5 The H. pylori Antigen Rapid Test Cassette (Feces) is a rapid chromatographic immunoassay for the qualitative detection of H. pylori antigens in human feces specimens, providing results in 10 minutes. The test utilizes antibodies specific for H. pylori antigens to selectively detect H. pylori antigens in human feces specimens.

1.What does rapid testing reveal? Rapid tests tell us if a patient is actively infected. They detect the presence of target from patient specimens. Results are produced quickly, generally within 15 minutes, and can be performed near the place and time of patient care (as opposed to a separate laboratory setting). If the target object is detected, it indicates that immediate action should be taken. 2.Is there an accuracy concern with rapid testing? These tests are generally less sensitive than molecular tests, and it's important to be aware that there is an increased possibility of false negatives with rapid testing. They are most accurate when viral loads are high (within the first couple of symptomatic days), and your healthcare provider may order a molecular test to confirm the results of your rapid test if it indicates that you are negative. If your rapid test is positive, there is no need to confirm with a molecular test, as these tests are highly specific.

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