Dengue NS1 Antigen Rapid Test Kit

Short Description:

A rapid test for a qualitative test for the detection of NS1 antigen of dengue virus in human whole blood,serum or plasma.

MOQ:1000 pcs

Price: Starting at $0.25/PCS

Certificate: CE ISO

OEM/ODM: Acceptable


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【SUMMARY】

  Dengue is a flavivirus, transmitted by Aedes aegypti and Aedes albopictus mosquitoes. It is widely distributed throughout the tropical and subtropical areas of the world,mostly in urban and semi-urban areas.Dengue causes up to 100 million infections annually.Today,about 2.5billion people live in areas where there is a risk of dengue transmission.Clinic feature of Dengue infection are sudden onset of fever, intense headache, myalgia, arthralgia and rash.It is the most severe arbovirus disease that causes human morbidity and death.NS1 is one of seven Dengue Virus non-structural proteins which are thought to be involved in viral replication.NS1 exists as a monomer in its immature form but is rapidly processed in the endoplasmic reticulum to form a stable dimer.It allows rapid detection on the first day of fever, before antibodies appear some 5 or more days later. A small amount of NS1 remains associated with intracellular organelles where it is thought to be involved in viral replication. The rest of NS1 is found either associated with the plasma membrane or secreted as a soluble hexadimer. NS1 is essential for viral viability but its precise biological function is unknown.Antibodies raised in response to NS1 in viral infection can cross react with cell surface antigens on epithelialcells and platelets and this has been implicated in the development of Dengue Hemorrhagic fever.Early detection and access to proper medical care can lower fatality below 1%.

  The Dengue NS1 Rapid Test Cassette (Whole Blood/Serum/Plasma) is a rapid test that utilizes a combination of Dengue antibodies coated colored particles for the detection of Dengue NS1 antigen in human whole blood, serum, or plasma.It has been compared with a leading commercial Dengue Ag EIA test. The correlation between these two systems is 96.1%.

 

【PRINCIPLE】

  The Dengue NS1 Rapid Test Cassette(Whole Blood/Serum/Plasma) is a qualitative membrane-based immunoassay for the detection of Dengue NS1 antigen in whole blood, serum, or plasma. During testing, the specimen reacts with Dengue antibody-conjugate in the test cassette. The Gold antibody conjugate will bind to Dengue antigen in the specimen sample which in turn will bind with Anti-Dengue NS1 coated on the membrane. As the reagent moves across the membrane, the Dengue NS1 antibody on the membrane will bind the antibody-antigen complex causing pale or dark pink line to form at the test line region of the test membrane. The intensity of the lines will vary depending upon the amount of antigen present in the sample. The appearance of pink line in the test region should be considered as positive result.

【STORAGE AND STABILITY】

  The kit can be stored at room temperature or refrigerated (2-30°C). The test cassette is stable through the expiration date printed on the sealed pouch. The test cassette must remain in the sealed pouch until use. DO NOT FREEZE. Do not use beyond the expiration date.
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