Calprotectin Semi-Quantitative Rapid Test Kit

Short Description:

A rapid test for the semi-quantitative detection of Calprotectin in feces.


MOQ:1000 pcs


Product Detail

FAQ

Product Tags

SUMMARY

Calprotectin, first described in 1980, is aprotein found in the cytosol of neutrophils and macrophages composed of two subunits S100A8 and S100A9. It is released extracellularly in times of cell stress or damage and can be detected within feces and thus can be used as a sensitive marker of intestinal inflammation. It is stable in feces for up to seven days at room temperature and has a homogenous distribution in feces, properties which lend it to testing spot fecal samples.The inflammatory bowel diseases (IBD), Crohns diseaseand ulcerative colitis, are chronic relapsing, remitting disorders. Diagnosis along with assessment of disease activity and prognosis present challenges to managing clinicians. Fecal biomarkers, such as fecal calprotectin, are a non-invasive method which can be used to aid the sedecisions. Fecalprotectin has been shown to be useful in the diagnosis of IBD, correlates with bowel mucosal disease activity and can help to predict response to treatment or relapse. With growing evidence supporting its use, over the last decade this fecal biomarker has significantly changed the way IBD is managed.

PRINCIPLE

The Calprotectin Semi-Quantitative Rapid Test Cassette (feces) detects Calprotectin through visual interpretation of color development on the internal strip. Anti-Calprotectin antibodies are immobilized on the test region of the membrane. During testing, the specimen reacts with anti-Calprotectin antibodies conjugated to colored particles and precoated on the sample pad of the test. The mixture then migrates through the membrane by capillary action, and interacts with reagents on the membrane. If Test line 1 (T1) appears, it indicates that the Calprotectin level in the specimen is below 15ug/g. If the test line 1 and 2 (T1 and T2) appear, it indicates that the Calprotectin level in the specimen is between 15-60ug/g. If all the test lines (T1, T2, T3) appear, it indicates that the Calprotectin level is above 60ug/g. The appearance of control line serves as a procedural control, indicating that the proper volume of specimen has been added and membrane wicking has occurred.

STORAGE AND STABILITY

The kit can be stored at room temperature or refrigerated (2-30°C). The test cassette is stable through the expiration date printed on the sealed pouch. The test cassette must remain in the sealed pouch until use. DO NOT FREEZE. Don’t use beyond the expiration date.

Write your message here and send it to us